Peer-reviewed papers

L. Xing, J.M. Simon, T.S. Ptacek, J.J. Yi, L. Loo, H. Mao, J.M. Wolter, E.S. McCoy, S.R. Paranjape, B. Taylor-Blake, M.J. Zylka (2023). Autism-linked UBE3A gain-of-function mutation causes interneuron and behavioral phenotypes when inherited maternally or paternally in mice. Cell Reports. PMID: 37389991.

J. Xu, H.L. Farsad, Y. Hou, K. Barclay, B.A. Lopez, S. Yamada, I.O. Saliu, Y. Shi, W.C. Knight, R.J. Bateman, T.L.S. Benzinger, J.J. Yi, Q. Li, T. Wang, J.S. Perlmutter, J.C. Morris, G. Zhao (2023). Human striatal glia differentially contribute to AD and PD-specific neurodegeneration. Nature Aging. PMID: 36993867.

J.A. Stelzer, J.J. Yi (2022). A scalable, cell-based method for the functional assessment of Ube3a variants. Journal of Visualized Experiments. PMID: 36282706.

K.P. Weston, X. Gao, J. Zhao, K-S. Kim, S.E. Maloney, J. Gotoff, S. Parikh, Y.C. Leu, K.P. Wu, M. Shinawi, J.P. Steimel, J.S. Harrison, J.J. Yi (2021). Identification of disease-linked hyperactivating mutations in UBE3A through large-scale functional variant analysis. Nature Communications PMID: 34815418.

J.J. Yi, S.R. Paranjape, M.P. Walker, R. Choudhury, J.M. Wolter, G. Fragola, M.J. Emanuele, M.B. Major, M.J. Zylka (2017).  The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/beta-catenin pathway by inhibiting the proteasome.  The Journal of Biological Chemistry PMID: 28559284.

J.J. Yi, J. Berrios, J.M. Newbern, W.D. Snider, B.D. Philpot, K.M. Hahn, M.J. Zylka (2015).  An Autism-linked mutation disables phosphorylation control of UBE3A (2015).  Cell. PMID: 26255772.

E. McCoy, S. Street, B. Taylor-Blake, J. Yi, M. Edwards, M. Wightman, M. Zylka (2014). Deletion of ENTPD3 does not impair nucleotide hydrolysis in somatosensory neurons or spinal cord.  F1000 Research.  3:163, PMID: 25717362.

J. J. Yi, H. Wang, M. Vilela, G. Danuser, K.M. Hahn (2014).  Manipulation of endogenous kinase activity in living cells using photoswitchable inhibitory peptides.  ACS Synthetic Biology.  3:788 – 795.  PMID:24905630

A.V. Karginov, D. Tsygankov, M.E. Berginski, P.-H. Chu, E.D. Trudeau, J.J. Yi, S. Gomez, T.C. Elston, K.M. Hahn (2014).  Dissecting motility signaling through activation of specific Src-effector complexes.  Nature Chemical Biology.  10:286-90.  PMID: 24609359.

B.R. Arenkiel, H. Hasegawa, J.J. Yi, R.S. Larsen, M.L. Wallace, B.D. Philpot, F. Wang, M.D. Ehlers (2011).  Activity induced remodeling of olfactory bulb microcircuits revealed by monosynaptic tracing.  PLoS One.  6:29423.  PMID: 22216277

J.J. Yi, A.P. Barnes, R. Hand, F. Polleux, M.D. Ehlers (2010).  TGF-beta signaling specifies axons during brain development.  Cell.  142:144 – 57.  PMID: 20603020.

J.J. Yi and M.D. Ehlers (2007).  Emerging roles of ubiquitin and protein degradation in neuronal function.  Pharmacological Reviews.  59:14 – 39.  PMID: 17329546.

A.C. Horton, J.J. Yi, M.D. Ehlers (2006).  Cell type specific dendritic polarity in the absence of spatially organized external cues.  Brain Cell Biology.  25:29 – 38.  PMID: 17940911.

J.J. Yi and M.D. Ehlers (2005).  Ubiquitin and protein turnover in synapse function.  Neuron.  47:629 – 632.  PMID: 16129392.

J.J. Yi and M.D. Ehlers (2005).  Targeting protein degradation in the nervous system.  Current Medicinal Chemistry – Central Nervous System Agents, 5:285 – 306.

 

Book Chapters

E.C. O'Shaughnessy, J.J. Yi, K.M. Hahn. Optical Probes in Biology. J. Zhang, S. Mehta, C. Schultz, editors. Boca Raton, FL: CRC Press; 2014. Chapter 5, Biosensors of Small GTPase Proteins for Use in Living Cells and Animals; p.137-165.